Question
Which one of the following medications is most likely to be responsible for this finding?
- Amiodarone
- Cinacalcet
- Lithium
- Palifermin
- Trastuzumab
Correct Answer : Palifermin Explanation :
Palifermin, a recombinant keratinocyte growth factor, is used for the prevention of oral mucosal injury induced by cytotoxic therapy in patients undergoing hematopoietic stem-cell transplantation. Palifermin stimulates the proliferation and differentiation of epithelial cells. The white tongue is commonly observed in patients treated with palifermin and most likely reflects transient, protective mucosal thickening.